1. Its safety.
2. As far as I know, it can get anywhere in the aqueous compartments in the body.
3. Excesses are aggressively excreted without having to be metabolized first. Yes, aggressive excretion of a substance can be used to advantage!
Needed: an amphipathic chelator (could be excreted in urine), or a complementary lipophilic chelator (would need metabolism to be excreted in urine), at least as good as vitamin C – with the same aggressive excretion profile of any excesses.
Is lipoic acid about as safe an amphipathic chelator as vitamin C is a water-soluble chelator?
Modest excesses of vitamin C are good for kidney function. Since heavy metals are so harmful to the kidneys, is chelation one of the benefits (better solubilizing of the contents of urine being another) to the kidneys that comes from rapidly excreting vitamin C?