Does Helicobacter explore the lumen when the pH is safe?

I don’t know but I would guess it would in order to feed. Not much food behind the protective layer of mucus in the stomach.

If it gets coated with fat and this disrupts its communications, including of course its ability to sense pH gradients, it could be killed the next time it explores the lumen before significant protein digestion has raised the pH to a safe level, provided there is a sufficient amount of digested fat in the lumen.

 

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