When is a sensor not a good sensor?

When it is poisoned by excesses of harmful reagents and when it is starving for nutrients essential to its function.

An example: when is an oxygen sensor not a good oxygen sensor?

When oxygen is plentiful and the oxygen sensor “thinks” it is not because of either of the above problems.

Is a critical deficiency for the HIF oxygen sensor vitamin C? Can iron deficiency, alpha-ketoglutarate deficiency, and succinate excesses also be problematic to the function of this sensor? We know von Hippel Lindau factor deficiency is a problem as far as turning over HIF when oxygen is plentiful, and no doubt the proline hydroxylase deficiency is as well.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s