24 hour urinary excretion of taurine has an inverse hyperbolic relation to age-adjusted risk of ischemic heart disease

Taurine is abundant in seafood and countries that consume more seafood tend to have higher levels of taurine in plasma and in 24 hour urine samples.

The following study (PMID:11510759) shows a huge hyperbolic inverse relationship (incredibly they model the data as a straight line) between taurine levels in 24 hour urine samples (likely mostly reflective of dietary intake, although genetic variance among the diverse populations studied is no doubt also relevant) and the age-adjusted risk of ischemic heart disease.

Hypertens Res. 2001 Jul;24(4):453-7.

Distribution of twenty-four hour urinary taurine excretion and association with ischemic heart disease mortality in 24 populations of 16 countries: results from the WHO-CARDIAC study.

And here is the key graph:

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