Had Coley worded his cure slightly differently, the approach might still be being pursued with vigor:
The most aggressive and successful tumors are aided and abetted by the immune system. To kill these tumors, the immune system must be reprogrammed to aggressively attack the tumors. There are many ways to reprogram the immune system, starting with all natural method of inducing a strong, but controlled fever.
This wording is not so fever-centric as Coley’s – the method starts with fever but can branch out to less risky alternatives. Unfortunately, some oncologists see fever as wholly negative and would inevitably shun Coley’s method. A more balanced view of fever is that it has good and bad consequences and if the fever is controlled properly, fever could be a useful weapon against cancer even today, and it could be combined with complementary methods like a ketogenic diet.